What is ARIA?
An overview of ARIA Family Navigator — what it does, who it's for, and how it helps.
What is ARIA Family Navigator?
ARIA (Adaptive Research & Intelligence Assistant) is a free desktop application built for families of children with STXBP1 encephalopathy and 14 other rare neurological conditions. It combines AI-powered chat, medical document generation, genomic variant analysis, and a self-driving laboratory platform in one app.
What Can ARIA Do?
ARIA has five specialized modes, each designed for a different aspect of rare disease navigation:
- Paperwork Mode — Draft insurance appeal letters, medical necessity letters, and prior authorization forms using language optimized for approval.
- Research Mode — Search PubMed, ClinicalTrials.gov, and bioRxiv. Explore your child’s protein in 3D. Access 17,000+ curated research papers via RAG.
- Navigation Mode — Step-by-step guides for Medicaid, SSI, IEPs, and waivers — customized to your state and situation.
- General Chat — Open conversation for questions, emotional support, or medical terminology explained simply.
- Self-Driving Lab — Design CRISPR experiments, control lab equipment, and run automated protocols for researchers.
Who Built This?
ARIA was created by Adam Freygang, father of Katelyn (STXBP1 variant K196X), because navigating the medical, insurance, and educational systems for a child with a rare disease is overwhelming. The app is free, open, and funded entirely by the STXBP1 Foundation.