Getting Started

Set up ARIA, configure your API key, create your family profile, and start your first conversation!

Your First Tour

The three-pane layout, caregiver vs researcher vs lab starting paths, tips for your first week.

System requirements, download, first-launch onboarding, optional Google sign-in or PIN.

ARIA is a free desktop app for rare disease families combining AI chat, document generation, and genomic analysis.

Get your Anthropic API key, paste it in Settings, choose a model, and optionally add an NVIDIA key for protein tools.

ARIA has five specialized chat modes. Each mode activates different tools and changes how Claude approaches your question.

Your profile, chat history, and documents stay on your computer. Only conversation content goes to Anthropic via API.